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News
Recurrence Score Elevated for Breast Cancer Diagnosed Within First Year Postpartum
11+ hour, 16+ min ago (294+ words) Oncology Nurse Advisor HealthDay News — Postpartum breast cancer (PPBC) diagnosed within the first year postpartum has a significantly elevated 21-gene Oncotype DX Recurrence Score (RS), according to a study published online July 1 in npj Breast Cancer. Shiliang Zhang, M.D., from…...
Survival in Early Breast Cancer Without pCR Improved With Adjuvant Chemotherapy
8+ mon, 4+ day ago (304+ words) Patients with breast cancer who did not achieve a pathologic complete response (pCR) had better survival with adjuvant chemotherapy (ACT) than with neoadjuvant chemotherapy (NACT), according to results of a study published in The Oncologist. A growing body of evidence…...
Optimized Sequencing Advances Care for HR+/HER2+ Breast Cancer
8+ mon, 3+ week ago (419+ words) Recent phase 3 data and real-world experiences demonstrate that patient phenotype, comorbidities, and toxicity management all influence optimal sequencing in this biologically complex disease. In the phase 3 DESTINY-Breast09 trial, trastuzumab deruxtecan (T-DXd) plus pertuzumab achieved a median progression-free survival (PFS) of…...
Pertuzumab and Trastuzumab Maintain Long-Term Safety and Efficacy in Patients With Breast Cancer
11+ mon, 1+ week ago (280+ words) Subcutaneous delivery of fixed-dose pertuzumab and trastuzumab (PH FDC SC) was safe and well tolerated in patients with HER2-positive early breast cancer throughout 3 years of follow-up, according to continuation-phase results from the phase 2 PHranceSCa trial (NCT03674112) recently published in Clinical Breast…...
Breastfeeding Does Not Increase Risk of Recurrence or Death in Breast Cancer Survivors
11+ mon, 2+ week ago (309+ words) New data suggest that breastfeeding is safe for patients with stage I-III breast cancer who have hormone receptor (HR)-positive disease or carry BRCA variants.1,2 The cumulative incidence of breast cancer events at 12 months was 1.1% among patients who breastfed and…...