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A Rare Cause of Breast Pain in Primary Care: Mondor's Disease Diagnosed in a Family Medicine Clinic
1+ day, 8+ hour ago (230+ words) Mondor's disease is a rare disease that presents as a superficial thrombophlebitis that most often occurs in breast tissue, but can also occur on the anterior chest wall, thoracoabdominal region, and even the penis. Mondor's disease generally presents as localized…...
Single-Cell Profiling Identifies the SPDEF/GAS5 Axis as a Potential Driver of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer
1+ week, 8+ hour ago (337+ words) Background Estrogen receptor-positive (ER+) breast cancer is the most prevalent breast cancer subtype, and tamoxifen remains the cornerstone of adjuvant endocrine therapy. However, a significant proportion of patients eventually develop acquired tamoxifen resistance, leading to disease recurrence and progression. Methodology…...
Burden and Associated Factors of Anaemia Among Rural School-Going Adolescent Girls in North Coastal Andhra Pradesh, India: A Cross-Sectional Study
1+ week, 8+ hour ago (142+ words) Background Anaemia remains a major public health problem among adolescent girls, particularly in low- and middle-income countries. Adolescence is associated with increased iron requirements due to rapid growth and the onset of menarche. In India, anaemia prevalence remains high despite…...
Postpartum Insurance Coverage and Its Impact on Maternal Morbidity and Mortality Within the First Year After Delivery: A Scoping Review
1+ week, 3+ day ago (191+ words) Published by Dr. Kiran C. Patel College of Osteopathic Medicine (KPCOM) via the FLAGSHIP: Medical Scholarly Proceedings channel. Objectives: The primary objectives of this study are to identify current themes in literature on private versus public insurance coverage and their impact…...
Evaluation of the Association Between Maternal Anemia, Oral Mucosal Changes, and Adverse Birth Outcomes Among Pregnant Women
2+ week, 3+ day ago (386+ words) Introduction: Maternal anemia remains a major public health concern associated with adverse maternal and neonatal outcomes worldwide. Oral mucosal changes are also commonly observed in anemic individuals and may reflect the systemic severity of nutritional and hematological deficiencies. This study…...
Prevalence, Maternal Risk Factors, and Neonatal Outcomes of Early-Onset Neonatal Septicemia: A Retrospective Study
2+ week, 6+ day ago (311+ words) Introduction Neonatal infections continue to pose major challenges in intensive care settings. This study aimed to evaluate the prevalence, maternal risk factors, neonatal characteristics, and clinical outcomes associated with early-onset neonatal septicemia in neonates admitted to the neonatal intensive care…...
Programmed Intermittent Epidural Bolus vs Continuous Epidural Infusion for Labor Analgesia: A Comparative Study of Maternal Satisfaction and Breakthrough Pain
3+ week, 4+ day ago (316+ words) Introduction Effective labor analgesia plays a crucial role in improving maternal comfort and the overall childbirth experience. The aim of the present study was to compare maternal satisfaction and breakthrough pain between programmed intermittent epidural bolus (PIEB) and continuous epidural…...
Association of Systemic Inflammatory Indices With Breast Cancer: A Cross-Sectional Analysis of National Health and Nutrition Examination Survey (NHANES) Data
3+ week, 5+ day ago (393+ words) Background: Breast cancer remains one of the leading causes of cancer-related morbidity and mortality among women worldwide. Systemic inflammatory indices derived from routine hematological parameters, including NLR, PLR, and SII, have recently gained attention as potential biomarkers associated with breast…...
Digital Tools for the Recognition and Triage of Abnormal Uterine Bleeding: A Narrative Review
3+ week, 5+ day ago (37+ words) Cureus Please note that by doing so you agree to be added to our monthly email newsletter distribution list. Download Cureus Media Kit...
Cardiovascular Safety of Next-Generation Antibody-Drug Conjugates in HER2-Low and Triple-Negative Breast Cancer: A Narrative Review (2020-2025)
1+ mon, 4+ day ago (142+ words) The clinical validation of the HER2-low phenotype has expanded eligibility for HER2-targeted antibody-drug conjugates (ADCs). Trastuzumab deruxtecan (T-DXd) introduces a novel cardiotoxicity profile driven by both HER2 inhibition and payload-mediated off-target injury. A narrative review of recent literature and pharmacovigilance reports…...