5+ hour, 56+ min ago   (693+ words) A cross-sectional study involving 3068 women aged 20-54 years found minipad-based HPV testing detected moderate precancerous cervical changes with 94.7% sensitivity and severe changes with 92.9% sensitivity, closely matching clinician-collected samples (92.1% and 85.7%, respectively), according to the study. "The results of this large-scale community-based study…...

5+ mon, 4+ week ago   (576+ words) Compared with fulvestrant alone, the combination prolonged median PFS for these patients by 11 months, according to results from the phase 3 TIFFANY trial. However, similar to existing CDK4/6 inhibitors, the tibremciclib-fulvestrant combination added to treatment side effects " including substantially higher rates of…...

5+ mon, 4+ week ago   (265+ words) DISCLOSURES August 13, 2025 We use clinicopathologic data in combination with gene expression tests to stratify risk, but this approach doesn't always provide us with the necessary information for determining the optimal adjuvant or neoadjuvant treatment. The adjuvant CDK4/6 inhibitor'trials will be helpful,…...

5+ mon, 4+ week ago   (394+ words) For decades, girls have been starting menstruation at increasingly younger ages. A new Harvard study has confirmed this trend, showing that the onset of first periods continues to occur progressively earlier. At the same time, it takes longer for menstrual…...

6+ mon, 1+ week ago   (368+ words) DISCLOSURES July 30, 2025 Since the risk of developing febrile neutropenia with T-DXd is low (" 10%), prophylactic granulocyte colony-stimulating factor is typically not indicated. For T-DXd, cardiac events were minimal in DESTINY-Breast01 and Breast03 trials, with few patients experiencing reversible LVEF reductions; no events…...

6+ mon, 2+ week ago   (219+ words) Edited by Vineeta Teotia Bone health management for older women with breast cancer receiving aromatase inhibitors (AIs) varied substantially across five UK hospitals. Despite the higher risk for fractures, women older than 80 years were less likely to receive DEXA scans…...

6+ mon, 2+ week ago   (173+ words) Edited by Devyani Gholap In a nationwide study of over 1.4 million singleton births, neonates of mothers with type 1 diabetes (T1D) had substantially higher odds of stillbirth, congenital malformations, preterm birth, hypoglycaemia, and neonatal death. "Neonates born to mothers with type 1 diabetes…...

6+ mon, 3+ week ago   (570+ words) Excess body weight is a well-known risk factor for breast cancer in postmenopausal women, but is the risk the same in women who also have cardiovascular disease (CVD) or type 2 diabetes? The short answer is no for CVD and yes for…...

6+ mon, 3+ week ago   (1783+ words) Anne H. Cross, MD; Riley Bove, MD Dr Bove's research focuses on digital health, sex and gender differences in MS, and improving access to neurologic care. And, important for today's discussion, she is a menopause expert in MS patients and the…...

6+ mon, 3+ week ago   (482+ words) A French study found that menstrual cup users had a 2.6 times higher risk for IUD displacement or expulsion, even after a single use. Menstrual Cup Use Linked to Increased IUD Displacement Risk A new study published in the journal Contraception…...